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Biological fermentation
Release time:
2022-05-19 19:47
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Technology Overview
Ceramic membranes, owing to their high separation precision, excellent efficiency, and resistance to biofouling, have become the technology of choice for clarifying bi fermentation broths. The specially developed ceramic membranes not only remove microbial cells, suspended solids, and colloids, but also effectively eliminate dissolved proteins, macromolecules, polysaccharides, and other components, thereby enabling the separation and purification of target products from the fermentation broth. By leveraging highly precise membrane‑based separation, this approach can significantly enhance the efficiency of downstream processing steps—such as resin adsorption and nanofiltration/reverse osmosis concentration—while reducing production costs.
Application areas
- Antibiotic Erythromycin, cephalosporins, colistin sulfate, streptomycin, vancomycin, kasugamycin, tylosin, rifamycins, mitomycin C. Cheating by taking the exam on behalf of another, etc.
- Amino acid : Lysine, phenylalanine, threonine, arginine, tryptophan, D-amino acids, leucine, L-serine, and others
- Organic acid ： L-lactic acid, citric acid, succinic acid, etc.
- Vitamin : Vitamin C. Vitamin B2, Vitamin B12, Vitamin K
- Enzyme preparation : Phytase, protease, amylase, mannanase, pullulanase, lactase, etc.
- Pharmaceutical intermediate : Nucleosides, prils, statins, etc.
Process Flow Diagram
Project Showcase
The process for treating cephalosporin C fermentation broth using membrane technology is shown in the figure below:
A certain pharmaceutical company
The research institution approved by Nanjing is also an independent legal entity of the first professional research institute of Jiangsu Industrial Technology Research Institute Membrane Science and Technology Research Institute, which is positioned as the organizer of membrane material industry cultivation.
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